Precautions

The schizophrenic patients can develop symptoms augmented by psychosis; the patients with the paranoid symptomatology can have an exaggeration of such symptoms. The depressed patients, particularly those with known manic-depressive illness, can know a change in habit or in hypohabit. In these circumstances the dose of amitriptyline can be reduced or a tranquillizer importing such as perphenazine can be concurrently managed.

The possibility of suicide in the depressed patients stays until significant delivery occurs. The potentially suicidal patients should have no access to big quantities of this medicament. Prescripts should be written for the smallest accomplishable quantity.

The simultaneous administration of Amitriptyline and of electroshock therapy can augment chances linked to such therapy. Such treatment should be limited to the patients for whom it is essential.

When possible, the medicament should be stopped several days before the elective surgery.

Both elevation and fall of levels of glycemia were announced. Amitriptyline should be used with caution in the patients with the weak function of liver.