Warnings

Amitriptyline can block the antihypertensive action of guanethidine or similarly active compounds.

It should be used with caution in the patients with a history of seizures and, because of its atropine - as action, in the patients with a history of urinary retention, glaucoma of closing of assemblage or augmented intraoculaire pressure. In the patients with the glaucoma of closing of assemblage, the even medium doses can throw an attack.

Should be look one nearly at the patients with cardiovascular riot. They announced that medicaments of antidepressant of Tricyclic, by including amitriptyline, particularly when given in high doses, produce arrhythmias, sinus tachycardia and the extension of the time of conduction. Heart attack of Myocardial and blow were announced with medicaments of this class.

Close surveillance is demanded when amitriptyline is given to the patients of hyperthyroid or those who accept the treatment of thyroid.

Amitriptyline can improve the answer to the alcohol and to the effects of barbiturates and of other DÉPRESSEURS CNS. In the patients who can use some alcohol exceedingly, he should be kept in the head that the potentiation can augment inherent danger in any suicide attempt or excessive dose. Frenzy was announced with the simultaneous administration of amitriptyline and of disulfiram.

Usage in the Pregnancy

They showed that Amitriptyline crosses the afterbirth. Although a causative report is not established, there were some reports of disadvantageous events, by including effects of CNS, deformities of member, or delay of development, in the babies whose mothers had taken amitriptyline during the pregnancy. Amitriptyline should be used during the pregnancy only if the potential advantage to the mother justifies potential risk in the foetus.

Because of potential for serious disadvantageous reactions in the babies male nurses of amitriptyline, a decision should be made if it is necessary to stop care male nurses or to stop the medicament, by taking into account the importance of the medicament to the mother.

Usage at the Children: In view of the inexperience with the use of this medicament at the children, are not currently recommended for the patients less than 12 years of age.